Social Modulation of Pain as Evidence for Empathy in Mice

By Dale J. Langford, S. Crager, Zarrar Shehzad, Shad B. Smith, S. Sotocinal, Jeremy S Levenstadt, M. Chanda, Daniel J. Levitin, J. Mogil. Science, 2006

810 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Sensory Systems, Social Psychology

View Paper: https://www.semanticscholar.org/paper/08ecec36db860292fd90ffb0cda41d95b6b1d42f

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Citations in the corpus

Pain and Emotion: A Biopsychosocial Review of Recent Research (2011, positive): “For example, Langford et al. (2006) found that mice exposed to cage-mates in pain also displayed pain behaviors themselves, but this reaction did not occur when exposed to noncage-mates in pain.”
Social learning of fear (2007, background): “Indeed, in mice, observing a familiar, but not an unfamiliar, mouse experiencing pain enhances sensitization to pain at a later test tim”
The Many Faces of Empathy: Parsing Empathic Phenomena through a Proximate, Dynamic-Systems View of Representing the Other in the Self (2012, positive): “…shown to produce the psychophysiological orienting response associated with empathic concern in humans (Chen, Panksepp, & Lahvis, 2009) and to directly augment the experience of pain in observing mice, particularly for animals who were familiar or had experienced the pain (Langford et al., 2006).”
Empathy: Gender effects in brain and behavior (2014, background): “A uthor M anuscript A uthor M anuscript A uthor M anuscript A uthor M anuscript appear to increase their writhing when viewing a familiar individual in pain (Langford et al., 2006).”
Animal pleasure and its moral significance (2009, background): “Mice show empathy (Langford et al., 2006), sheep respond to the emotional states of other sheep (Da Costa et al., 2004), monkeys show a sense of justice (Brosnan and de Waal, 2003), starlings can become optimistic or pessimistic (Bateson and Matheson, 2007; Matheson et al., 2007), and rats show…”
From Mind Perception to Mental Connection: Synchrony as a Mechanism for Social Understanding (2012, background): “This tendency appears to be hardwired, as one day old infants cry upon hearing others cry (Singer, 2006), and evolutionarily old, as mice display pain symptoms when viewing their cage mates experience pain (Langford et al., 2006).”
Behavioural phenotyping assays for mouse models of autism (2010, background): “Subject mice show greater responsiveness to a painful experience after observing cagemates who have experienced a painful stimulu”
Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC (2010, background): “, empathy might be engaged in observational social fear learning, as in the case of the social modulation of pai”