Magnetic tweezers: micromanipulation and force measurement at the molecular level.

By C. Gosse, V. Croquette. Biophysical Journal, 2002

913 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy (2008, background): “The lateral position of the bead is determined from the centroid of the interference pattern, and the axial position of the bead is determined from the intensity distribution of the interference pattern, which is a strong function of the position of the bead with respect to the focus of the objectiv”
OctoMag: An Electromagnetic System for 5-DOF Wireless Micromanipulation (2010, background): “have created electromagnetic systems for 3-DOF manipulation of small magnetic particles in fluid under a microscope [28], [29], and others have demonstrated 3-DOF manipulation of a microrobot levitated in air [30].”
The biomechanics toolbox: experimental approaches for living cells and biomolecules (2003, background): “These beads can be attached through ligand-specific or aspecific binding to a cell surface for single cell studies [23,25,26], or attached through specific chemical functionalization to one end of nucleic acids [83,84] or biomolecules [85] that are fixed at the other end to a rigid surface.”
Microrheology of complex fluids (2005, methodology): “The fluctuation spectrum of the spheres in the trapping potential can be considered in much the same fashion as with optical tweezers, but the strength of the magnetic field can also be studied in situ from point to point using Hall probes (Gosse and Croquette 2002).”