Reconstructing and Deconstructing Agonist-Induced Activation of Integrin αIIbβ3
By Jaewon Han, C. Lim, N. Watanabe, A. Soriani, B. Ratnikov, D. Calderwood, W. Puzon‐McLaughlin, Esther M. Lafuente, V. Boussiotis, S. Shattil and 1 more. 2006
488 citations recorded by the source corpus.
Subfields: Cell Biology, Hematology, Immunology and Allergy
View Paper: https://www.semanticscholar.org/paper/08b27dc9f4944c5e8726741daef597e4d7d5d0dd
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Citations in the corpus
- Integrin signalling at a glance (2009, background): “This results in formation of a complex that contains talin and the Rap1 effector Rap1interacting molecule (RIAM) and that presumably activates talin and results in its targeting to integrins and integrin activation (Han et al., 2006; Watanabe et al., 2008).”
- The final steps of integrin activation: the end game (2010, background): “Its use in combination with forward and reverse genetics enabled the dissection of a pathway to integrin activatio”
- Integrins in cancer: biological implications and therapeutic opportunities (2010, unknown): “Increased affinity or activation can be induced by either ligand-mediated integrin clustering on the cell surface or increased intracellular signalling through molecules, such as the GTPase RAP1A”