Integrin signalling at a glance

By David S. Harburger, D. Calderwood. Journal of Cell Science, 2009

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Integrin Structure and Function (2010, background): “Src is a nonreceptor tyrosine kinase constitutively associated with the cytoplasmic tail of b3 integrins via its SH3 domains (Harburger and Calderwood 2009).”
The extracellular matrix at a glance (2010, background): “Cell adhesion to the ECM is mediated by ECM receptors, such as integrins, discoidin domain receptors and syndecans (Harburger and Calderwood, 2009; Humphries et al., 2006; Leitinger and Hohenester, 2007; Xian et al., 2010).”
Role of Extracellular Matrix in Development and Cancer Progression (2018, background): “The selective activation of these pathways leads to context-dependent regulation of cell survival, growth, proliferation, motility, spreading, or migration [52,58].”
Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance (2017, background): “Integrin Receptors Integrin receptors are large transmembrane glycoproteins that are made up of non-covalently associated α and β subunits and are present in virtually all mammalian cells (Harburger and Calderwood, 2009; Campbell and Humphries, 2011).”