Genetic rescue to the rescue.

By Sarah W. Fitzpatrick. Trends in Ecology & Evolution, 2015

745 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/087a59e5951db395681bc0a96614f12acb332eea

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. R. Frankham
2. A. Hoffmann
3. R. Lacy
4. P. Hedrick
5. J. Ballou
6. C. Fenster
7. K. Ralls
8. P. Sunnucks

In Molecular Biology

1. R. Frankham
2. R. Lacy
3. W. Chan
4. A. Hoffmann
5. Loren H. Rieseberg
6. R. Peterson
7. M. Oppen
8. P. Hedrick

Citations in the corpus

• Genetic factors in threatened species recovery plans on three continents (2016, background): “Genetic rescue of small populations (Whiteley et al. 2015) is often a goal of recovery actions such as translocations or augmentation (Weeks et al.”
• Hybridization and extinction (2016, background): “Any outbreeding depression must be outweighed by the fitness benefits of hybridization, for example, by compensating for deleterious mutations that have accumulated in an inbred population (Frankham et al. 2011; Whiteley et al. 2015) or locally adaptive immigrant alleles (Aitken and Whitlock 2013).”
• Call for a Paradigm Shift in the Genetic Management of Fragmented Populations (2018, background): “It is thus surprising that only about 30 “genetic rescues” of wild plant and animal populations have been attempted for conservation purposes, despite some spectacular, well-publicized successful examples such as Florida panthers (Puma concolor) (Johnson et al. 2010; Frankham 2015; Whiteley et al. 2”
• Genetic rescue of small inbred populations: meta-analysis reveals large and consistent benefits of gene flow. (2015, background): “Genetic theory indicates that it should often be possible to genetically rescue such populations by outcrossing within species (augmenting gene flow: Tallmon et al. 2004; Whiteley et al. 2015).”
• Hybridization as a conservation management tool (2019, methodology): “Hybridization may bring evolutionary rescue when a shift toward the optimal phenotype occurs via selection on the newly introduced or recombinant later generation hybrid genotypes (Carlson et al., 2014; Whiteley et al., 2015).”
• Genetics and extinction and the example of Isle Royale wolves (2019, background): “…to overcome the impact of lowered fitness is genetic rescue in which the natural or artificial introduction of individuals from outside the population provides genetic variation that subsequently results in higher fitness (Tallmon et al., 2004; Whiteley et al., 2015; Hedrick & Garcia-Dorado, 2016).”
• Unbiased population heterozygosity estimates from genome-wide sequence data (2020, background): “…action involves selecting populations for genetic and evolutionary rescue, which aims to decrease levels of inbreeding and increase levels of genetic variation in target populations through targeted introductions of individuals from other populations (Hoffmann et al., 2020; Whiteley et al., 2015).”