The tight junction: a multifunctional complex.
By E. Schneeberger, R. Lynch. American Journal of Physiology - Cell Physiology, 2004
1,435 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology, Neurology
View Paper: https://www.semanticscholar.org/paper/0853a538372ac92cd400628781948ba0a55c714e
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
In Molecular Biology
- J. Turner
- Carola Förster
- C. Niessen
- M. Furuse
- Andrea Hartsock
- S. Tsukita
- W. Nelson
- Junichi Ikenouchi
In Neurology
- J. Turner
- Carola Förster
- C. Niessen
- M. Furuse
- S. Tsukita
- Takuya Suzuki
- C. V. Van Itallie
- James M. Anderson
Citations in the corpus
- Tight junctions and the modulation of barrier function in disease (2008, background): “Mounting evidence suggests that the cytosolic TJ plaque is one of the sites in which such signaling is coordinated (Ebnet 2008; Gonzalez-Mariscal et al. 2003; Schneeberger and Lynch 2004).”
- The blood-brain barrier in Alzheimer's disease (2017, neutral): “Occludin is a transmembrane protein found in TJs, which anchors the cytoplasmic zona occludens (ZO) proteins 1 and 2 and the plasma membranes of adjacent cells (Furuse et al., 1993; Schneeberger and Lynch, 2004).”
- Regulation of retinal blood flow in health and disease. (2008, background): “The plaque itself is anchored to the actin cytoskeleton and to various signaling molecules that participate in the control of cell proliferation and differentiation (Tsukita et al., 2001; D’Atri and Citi, 2002; Schneeberger and Lynch, 2004; Aijaz et al., 2006; Bazzoni, 2006).”
- Epithelial barriers in homeostasis and disease. (2010, background): “Several other groups of proteins, including transmembrane, cytoskeletal, and signaling proteins (20), are present at the tight junction.”
- Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells (2005, background): “Tight junctions (TJs) prevent the leakage of solutes through the paracellular pathway of epithelial cells (Tsukita et al., 2001; Matter and Balda, 2003; Anderson et al., 2004; Schneeberger and Lynch, 2004) and are indispensable in establishing the various compositionally distinct fluid compartments ”
- Tight junctions/adherens junctions: basic structure and function. (2007, background): “These proteins can interact directly with occludin and claudins via their PDZ domains, whereas their C-terminus can associate with actin, thus providing a direct link with the cytoskeleton (Schneeberger and Lynch, 2004).”
- Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. (2008, background): “Claudin The claudin family consists of at least 24 members ranging from 20 to 27 kDa [5,91] (Fig.”
- Crosstalk of tight junction components with signaling pathways. (2008, background): “The former mediate cell–cell adhesion, while the latter function as a bridge between the TJ and the actin cytoskeleton (for extensive reviews, see [8,9]).”