Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma

By C. Nemeroff, Christine Marcelle Heim, M. Thase, D. Klein, A. Rush, A. Schatzberg, P. Ninan, J. P. Mccullough, Paul M. Weiss, D. Dunner and 4 more. Proceedings of the National Academy of Sciences of the United States of America, 2003

810 citations recorded by the source corpus.

Subfields: Clinical Psychology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/07b55a8b4e942e11a04a6bce20c08c5cd3900217

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Citations in the corpus

The link between childhood trauma and depression: insights from HPA axis studies in humans. (2008, background): “The likelihood to achieve remission in psychotherapy versus nefazodone was two times higher for depressed patients with childhood trauma and three times higher specifically for those with parental loss (Nemeroff et al., 2003).”
Neurobiological and psychiatric consequences of child abuse and neglect. (2010, methodology): “Nemeroff et al. (2003) addressed this important question by reanalyzing data from a large, multicenter, double-blind randomized controlled trial.”
Immune System to Brain Signaling: Neuropsychopharmacological Implications (2011, background): “…with non-response to treatment with conventional antidepressant medications as well as early life stress, which is likewise associated with an antidepressant treatment non response (Sluzewska et al., 1997; Lanquillon et al., 2000; Nemeroff et al., 2003; Danese et al., 2007; Danese et al., 2008).”
Disorders of extreme stress: The empirical foundation of a complex adaptation to trauma. (2005, background): “For example, there is increasing evidence that having a history of child abuse may significantly change treatment outcome in other psychiatric conditions (e.g., Ford & Kidd, 1998; Keller et al., 2000; Nemeroff et al., 2003).”
Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. (2012, neutral): “These subtypes of depression were also found to be responsive to differential treatments (Nemeroff et al., 2003).”
Posttraumatic stress disorder: a state-of-the-science review. (2006, result): “A secondary analysis (Nemeroff et al., 2003) of the data set from the foregoing study revealed several novel findings.”
Inflammatory Cytokines in Depression: Neurobiological Mechanisms and Therapeutic Implications (2013, background): “In fact, persons exposed to early life stress have been found to be less responsive to antidepressant interventions (Nemeroff et al., 2003, Nanni et al., 2011).”
Cognitive therapy vs. medications for depression: Treatment outcomes and neural mechanisms (2008, methodology): “, a variant of CT), using an important early-history variabl”
Treatment for Chronic Depression Using Schema Therapy (2013, positive): “Childhood adversity in the treatment of chronic depression is associated with decreased response to ADM (Hayden & Klein, 2001; Kaplan & Klinetob, 2000) and higher response rates to psychotherapy (Nemeroff et al., 2003).”
Paradise Lost: The Neurobiological and Clinical Consequences of Child Abuse and Neglect. (2016, background): “…that in a study of 808 patients with chronic depression, ELS predicted poor response to antidepressants including sertraline, escitalopram, bupropion, venlafaxine, ormirtazapine, an observation previously reported by Nemeroff et al. (2003) in chronically depressed patients treated with nefazodone.”