Multiple regions within 8q24 independently affect risk for prostate cancer

By C. Haiman, Nick Patterson, M. Freedman, S. Myers, M. Pike, Alicja Waliszewska, Julie Neubauer, Arti Tandon, Christine Schirmer, G. McDonald and 16 more. Nature Genetics, 2007

676 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0768718ad4ebf1bf400d554b4e18e7c6ed048dfe

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Citations in the corpus

International variation in prostate cancer incidence and mortality rates. (2012, neutral): “…differences such as variants in alleles on chromosomes including (but not limited to) 8q24 and 17q21 may be specific to men of African descent [41] [42] [43] in the United States and elsewhere, suggesting that the PCa disparity by race may partly be due to variations in genetic Table 2 –…”
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 (2007, background): “This locus has also been implicated in prostate cance”
Consistent Association of Type 2 Diabetes Risk Variants Found in Europeans in Diverse Racial and Ethnic Groups (2010, background): “For example, genetic variation at 8q24 may contribute to population differences in risk of prostate cancer [16,17], and genetic variation at MYH9 contributes substantially to the higher rates of kidney disease in African Americans [18].”
PGA: power calculator for case-control genetic association analyses (2008, background): “08 assuming a modest relative risk of ~2-fold as implied by the preliminary studies [15-17] (Figure 1B).”