Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells.

By M. Körbling, R. Katz, Abha Khanna, A. Ruifrok, G. Rondon, M. Albitar, R. Champlin, Z. Estrov. New England Journal of Medicine, 2002

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Plasticity of marrow-derived stem cells. (2003, positive): “In the human studies, donor derived keratinocytes were cytokeratin positive and CD45 negative.(33) However, even though 4-14% of keratinocytes in human skin were Y+, keratinocytes grown in vitro from the same skin biopsies failed to demonstrate any Y+ donor cells even when very sensitive PCR analysi”
In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. (2003, background): “This phenomenon of engraftment of bone marrow–derived cells into multiple tissues is also found in humans (29, 30).”
The role of hepatocytes and oval cells in liver regeneration and repopulation. (2003, background): “The higher frequency of liver cell production from HSC reported in a few cases needs to be confirmed using stringent confocal analysis and double labeling techniques (Korbling et al., 2002; Theise et al., 2000b).”