Cell types to order: temporal specification of CNS stem cells.

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Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Do putative adult neural stem cells display a temporally segregated sequence of symmetric self-renewal, neurogenesis, and gliogenesis as occurs during embryonic cortical development (reviewed by Okano and Temple, 2009)?”
Comprehensive analysis of retinal development at single cell resolution identifies NFI factors as essential for mitotic exit and specification of late-born cells (2018, background): “, 2014); and changes in developmental competence - the ability of NPCs to give rise to different subtypes of neurons and glia (Cayouette et al., 2013; Kohwi and Doe, 2013; Okano and Temple, 2009).”
Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila (2015, unknown): “Neural stem cells are critical for growth of themammalian CNS during development and also for neuronal turnover in the subventricular zone and dentate gyrus during adulthood (Okano and Temple, 2009; Taverna et al., 2014).”
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation (2017, unknown): “Mettl14 Deletion in Neural Progenitor Cells Leads to Protracted Cell-Cycle Progression Given the well-defined temporal progression of cortical neurogenesis from RGCs (Okano and Temple, 2009), we suspected that there could be RGC deficits during embryonic stages in cKO mice.”