Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation

By S. Back, T. Tuohy, Hanqin Chen, N. Wallingford, Andrew Craig, Jaime Struve, N. Luo, F. Banine, Ying Liu, Ansi Chang and 4 more. Nature Medicine, 2005

613 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/06278956fd271d68279471c53c0509d8f8d2c480

How researchers see this paper

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In Cell Biology

1. Nikolaos G. Frangogiannis
2. A. Varki

In Molecular Biology

1. C. ffrench-Constant
2. Robin J. M. Franklin
3. C. Iadecola
4. A. Varki

Citations in the corpus

• Hyaluronan as an Immune Regulator in Human Diseases (2011, positive): “HA accumulates in demyelinated lesions from individuals with multiple sclerosis and in mice with experimental autoimmune encephalomyelitis (16).”
• Remyelination in the CNS: from biology to therapy (2008, background): “The accumulation of the glycosaminoglycan hyaluronan, an inhibitor of OPC differentiation, in MS lesions might contribute to an environment in chronic lesions that is not conducive to remyelinatio”