Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.
By B. Sarkadi, L. Homolya, G. Szakács, A. Váradi. Physiological Reviews, 2006
738 citations recorded by the source corpus.
Subfields: Epidemiology, Infectious Diseases, Oncology
View Paper: https://www.semanticscholar.org/paper/050ad80f0a896c34f86a677a5aabdf1de20a9735
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In Oncology
Citations in the corpus
- Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs (2007, background): “Transporters that have been more frequently implicated in the intestinal efflux of drugs and lipid molecules include the multidrug resistance (MDR) transporter family, multidrug resistance-associated protein (MRP) transporter family and breast cancer resistance protein (BCRP from the ABCG2 gene”
- Mechanistic diversity in ATP-binding cassette (ABC) transporters (2016, background): “…transporters such as ABCB1, ABCG2, or ABCC1 protect various organs from toxic insult, but also contribute to drug resistance of cancer cells 14-17 ; In liver, a series of ABC transporters (ABCB11, ABCB4, ABCG5/G8) catalyzes the generation of bile, with dysfunction of either transporter…”