Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats.
By Li-Ru Zhao, W. Duan, M. Reyes, C. Keene, Catherine M. Verfaillie, Walter C. Low. Experimental Neurology, 2002
860 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Genetics
View Paper: https://www.semanticscholar.org/paper/04ccee113ca53654453745f53e16d9efc50a4256
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In Genetics
Citations in the corpus
- From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells (2007, background): “Moreover, in mice with acid sphingomyelinase deficit, MSC transplants delay the onset of neurological abnormalities and extend their lifespan (Chen et al., 2001; Jin et al., 2002; Zhao et al., 2002).”
- Autologous mesenchymal stem cell transplantation in stroke patients (2005, background): “Animal models of stroke have improved with MSC transplantation.(4,7,8) Although MSC infusion is a promising strategy to augment recovery from stroke, to our knowledge, transplantation of MSCs into stroke patients and the longterm effects of this approach have not been reported.”
- Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential (2004, background): “…developed mesodermalderived lineages (Reyes et al., 2001), they also developed ectodermal-derived lineages, such as immature neural-like cells and glial-like cells, in vivo (Zhao et al., 2002), as well as endodermal-derived lineages, such as hepatocyte-like cells, in vitro (Schwartz et al., 2002).”
- Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy (2004, background): “1A) has been challenged by the recent findings that adult stem cells can give rise to cells other than their residing tissues upon in vivo transplantation [58-60].”