The significance of vitamin D for fish: a review.
By E. Lock, R. Waagbø, S. W. Bonga, G. Flik. 2010
153 citations recorded by the source corpus.
Fish store large quantities of vitamin D in their liver and fat tissues, including the fat associated with muscle, and this makes fish an important dietary source of vitamin D. Fish do not synthesize vitamin D and are fully dependent on dietary sources to meet their requirement. Under natural circumstances planktonic vitamin D accumulates in the aquatic food chain. In aquaculture, formulated diets are used and vitamin D intake can be manipulated. The minimum dietary requirement for vitamin D has been established in several fish species. The role of vitamin D in fish physiology is still enigmatic. Till the 1970s there was consensus that fish accumulate but not metabolize vitamin D. There is substantial evidence now, four decades later, that fish have a vitamin D endocrine system with similar functions as in mammals. We here summarize the major characteristics of the fish vitamin D endocrine system. The hydroxylation of vitamin D to more polar metabolites, their plasma levels and protein-bound transport in blood plasma will be discussed. The vitamin D receptor profile, receptor distribution and responses to vitamin D are reviewed for the key target tissues (gill, intestine, kidney and bone). We will address the classical slower actions through transcription factors as well as the faster G-protein coupled (membrane) receptor mediated effects. We then review the dietary requirement of vitamin D in aquaculture and address some lesser known functions of the vitamin D endocrine system.
Subfields: Aquatic Science, Pathology and Forensic Medicine, Pediatrics, Perinatology and Child Health
View Paper: https://www.semanticscholar.org/paper/04290222a9a71d3d432f9b0c3149e2dd0302d9b3
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In Aquatic Science
- E. Gisbert
- Clara Boglione
- J. Zambonino-Infante
- G. Koumoundouros
- Paulo Jorge Gavaia
- E. Lock
- R. Waagbø
- R. Ørnsrud
Citations in the corpus
- Overview of vitamin D and C requirements in fish and their influence on the skeletal system (2011, background): “The origin and hydroxylation of vitamin D metabolites in fishes is provided in an excellent review of the significance of vitamin D for fish (Lock et al., 2010).”
- Skeletal anomalies in reared European fish larvae and juveniles. Part 1: normal and anomalous skeletogenic processes (2013, background): “…et al. 2004; Fjelldal et al. 2009, 2010), administered dietary phosphoglyceride classes (Tocher et al. 2008); inappropriate levels of vitamin D (Lock et al. 2010), vitamin A (Fern andez & Gisbert 2011; Georga et al. 2011; Fern andez et al. 2012), vitamin D and vitamin C (Darias et al. 2011);…”
- Skeletal anomalies in reared European fish larvae and juveniles. Part 2: main typologies, occurrences and causative factors (2013, background): “In contrast to mammals that are able to synthesize vitamin D from a cholesterol derivative through photosynthesis in the skin under ultraviolet B radiation exposure, fish cannot synthesize vitamin D from solar energy because all traces of irradiation are absorbed by sea water in the first few metres”
- Vertebral deformities in farmed Atlantic salmon (Salmo salar L.) – etiology and pathology (2012, background): “The vitamin D system is essential for efficient absorption of phosphorus (Lock et al., 2010) and sub-”