Crystal structure of metarhodopsin II

By H. Choe, Y. Kim, J. Park, T. Morizumi, E. Pai, N. Krauß, K. Hofmann, P. Scheerer, O. Ernst. Nature, 2011

650 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/040f39ed066b8a24d9adef816020edfb62b33789

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Brian K. Kobilka
2. William I. Weis
3. S. Rasmussen
4. M. von Zastrow
5. Raymond C. Stevens
6. Roderick E. Hubbard

In Molecular Biology

1. Debora Marks
2. Christopher Sander
3. Brian K. Kobilka
4. Lucy J. Colwell
5. Burkhard Rost
6. Thomas A. Hopf
7. David T. Jones
8. William I. Weis

Citations in the corpus

• Conical intersection dynamics of the primary photoisomerization event in vision (2010, background): “Detergent micelles have long been used as the microenvironment of choice for ultrafast spectral measurements [26, 53], where most recently n-dodecyl-β-D-maltopyranoside (DM) has become a commonly used detergent for this purpose [164], having been developed for use in leeching membrane proteins [165]”
• 3D structures of membrane proteins from genomic sequencing (2012, positive): “Despite great progress in determining structures by experimental methods (Chen et al., 2010; Cherezov et al., 2007; Choe et al., 2011; Long et al., 2007; Miller and Long, 2012; Rasmussen et al., 2011; Rasmussen et al., 2007), the 3D structures of most transmembrane proteins remain unknown, and…”
• Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance (2013, background): “Pioneering studies of rhodopsin (Choe et al., 2011) and the b2-adrenergic receptor (Rasmussen et al., 2011; Rosenbaum et al., 2011) provide interesting clues.”
• Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin (2012, positive): “It was also possible to determine the structure of opsin in complex with a signaling peptide of the corresponding G-protein (Scheerer et al., 2008) and of the light activated form, the all-transretinal bound metarhodopsin II (Choe et al., 2011) using BL14.”
• Crystal Structure of the β2Adrenergic Receptor-Gs protein complex (2011, positive): “Figure 6a,b compares the active-state structure of β 2 AR in the β 2 AR-Gs complex with the recent structure of metarhodopsin II bound to a peptide representing the carboxyl terminus of transducin 31 .”