Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

By Amy R. Cameron, V. Morrison, Daniel Levin, M. Mohan, C. Forteath, C. Beall, A. McNeilly, D. Balfour, T. Savinko, A. Wong and 6 more. Circulation Research, 2016

611 citations recorded by the source corpus.

Supplemental Digital Content is available in the text.

Subfields: Cancer Research, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/03b13e14d3ca6a78d4a27d76b7437696bb604a4c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. E. Pearson

In Epidemiology

1. D. Hardie

In Molecular Biology

1. Sriram Gubbi
2. Nir Barzilai
3. Ameya Sadguru Kulkarni
4. D. Hardie
5. R. Shaw
6. S. Hawley
7. David M. Sabatini
8. G. Steinberg

Citations in the corpus

• Benefits of Metformin in Attenuating the Hallmarks of Aging (2020, background): “A key consequence of this dysregulation is age-associated chronic, sterile, low-grade inflammatory state called inflammaging, that is usually accompanied by a consistent increase in pro-inflammatory cytokine secretion (TNF, IL-6, and IL-1β), activation of NF-κB and interferon signaling, increased bu”
• The mechanisms of action of metformin (2017, background): “In addition, metformin suppresses several inflammatory cytokines in human plasma in individuals without diabetes [53].”