Microbiological effects of sublethal levels of antibiotics

By D. Andersson, D. Hughes. Nature Reviews Microbiology, 2014

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Antibiotic-Resistance Genes in Waste Water. (2017, background): “It is now well established that even low concentrations of antibiotics can result in the selection of ARGs [47], which makes it very difficult to establish a safe concentration of an antibiotic compound in the waste water.”
Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections (2016, background): “Postulated stressors in the CF lung include osmotic stress [7] due to the viscous mucus, oxidative [8] and nitrosative [9] stresses due to host responses, sublethal concentrations of antibiotics [10], and the presence of other microorganisms [11,12].”
Antibiotic resistance: a rundown of a global crisis (2018, background): “Although very little has been reported in human pathogens about this aspect, production of enzymes (β-lactamases) is an exceptional example as a naturally present resistance mechanism and has an impact on human health.(31,32) It is considered that various antimicrobial molecules produced by saprophy”