Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
By Gerda Lagger, D. O’Carroll, Martina Rembold, Harald Khier, Julia Tischler, G. Weitzer, B. Schuettengruber, C. Hauser, R. Brunmeir, T. Jenuwein and 1 more. EMBO Journal, 2002
821 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/01e16b8dfa8a109790170102ac166961d355bf84
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In Molecular Biology
- E. Olson
- PA Marks
- J. Richardson
- Rusty L. Montgomery
- M. Haberland
- X. Qi
- Joseph A. Hill
- Pier Giuseppe Pelicci
Citations in the corpus
- The many roles of histone deacetylases in development and physiology: implications for disease and therapy (2009, background): “5) and display severe proliferation defects and general growth retardatio”
- The world of protein acetylation. (2016, background): “HDAC1-null mice display proliferation defects and growth retardation and die before embryonic day 10 [290,291].”
- Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. (2007, background): “1D; Lagger et al. 2002).”
- Histone Deacetylase Inhibitors: Overview and Perspectives (2007, background): “For example, HDAC1 knockout has a general proliferation and survival defect despite increased levels of HDAC2 and HDAC3 activity (10).”
- Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer (2006, background): “This shows a crucial, non-redundant role for HDAC1 in regulating cell proliferatio”