Bioavailability of curcumin: problems and promises.

By P. Anand, A. Kunnumakkara, R. Newman, Bharat B. Aggarwal. Molecular Pharmaceutics, 2007

5,311 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Medicine, Pharmacology

View Paper: https://www.semanticscholar.org/paper/01d71ae294672b7102b0bd4455af5d6fb677788b

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In Endocrinology, Diabetes and Metabolism

Bharat B. Aggarwal

In Molecular Medicine

In Pharmacology

Citations in the corpus

Curcumin: A Review of Its’ Effects on Human Health (2017, background): “major problems with ingesting curcumin by itself is its poor bioavailability [15], which appears to be primarily due to poor absorption, rapid metabolism, and rapid elimination.”
α-Terpineol, a natural monoterpene: A review of its biological properties (2018, background): “Because of the insufficient aqueous solubility and bioavailability of curcumin, it is not widely used in the clinical field for treatment of cancer and other diseases [74].”
Carotenoids: biochemistry, pharmacology and treatment (2016, background): “Despite the lower bioavailability of curcumin, its therapeutic efficiency has been proven in different human diseases including CVDs, diabetes, cancer, arthritis, Crohn’s disease and neurological diseases (Anand et al., 2007; Gupta et al., 2013).”
Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors. (2014, background): “the parent compound, such as liposomal, nanoparticulated, and phospholipid complex formulations of curcumin [250].”
Novel insights of dietary polyphenols and obesity. (2014, background): “After eating polyphenol-rich foods or taking dietary supplement, humans achieve peak plasma polyphenol concentrations at less than 10 μM [172,174–177].”
Identification of Amyloid Plaques in Retinas from Alzheimer’s Patients and Noninvasive In Vivo Optical Imaging of Retinal Plaques in a Mouse Model (2010, neutral): “Furthermore, recent studies have reported various approaches to significantly increase curcumin stability and bioavailability in humans (Anand et al., 2007).”