Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on…

By J. Walston, E. Hadley, Luigi Ferrucci, Jack M. Guralnik, Anne B. Newman, Stephanie A. Studenski, W. Ershler, Tamara B. Harris, L. Fried. Journal of The American Geriatrics Society, 2006

1,570 citations recorded by the source corpus.

Subfields: Aging, Geriatrics and Gerontology, Physiology

View Paper: https://www.semanticscholar.org/paper/011e75b03a080393c680c21a20ebdf1e58f67b07

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Citations in the corpus

The Identification of Frailty: A Systematic Literature Review (2011, background): “Whether exploring the etiologies and predictors of frailty, or interventions to prevent and treat frailty, researchers need a clear definition to define their study populations and measure their results.(8,9,16) Similarly, policy decisions regarding the distribution of scarce resources to help frail”
Frailty: an emerging research and clinical paradigm--issues and controversies. (2006, background): “The 2004 AGS/NIA conference proposed a detailed research agenda (8).”
Aging, frailty and age-related diseases (2010, background): “The causes of frailty are complex and must be accepted as multidimensional based on the interplay of genetic, biological, physical, psychological, social and environmental factors (Walston et al. 2006; Rockwood and Mitnitski 2007a, b).”
Outcome instruments to measure frailty: a systematic review. (2011, background): “Therefore, in the last few years, frailty is acknowledged to be not only a biological or physiological state, but also a multidimensional concept (Walston et al., 2006).”
A standard procedure for creating a frailty index (2008, background): “It indicates that frailty can be measured in many ways, and therefore can be studied in many existing datasets that might not have set out to measure frailty per se. To encourage more widespread evaluation of frailty – a goal encouraged by many groups [ 12-14 ] – we present a detailed, step-by-step ”
Postoperative Delirium in the Elderly: Risk Factors and Outcomes (2009, background): “Frailty characterizes the elderly patients excess vulnerability to a surgical stress.(6) Common phenotypes of frailty include cognitive dysfunction, functional impairment, poor nutrition, blood pressure instability, and weakness.”
Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review (2011, background): “A definition of frailty that is often used by geriatricians is the following: ‘a biologic syndrome of decreased reserve and resistance to stressors, resulting from cumulative decline across multiple physiologic systems, and causing vulnerability to adverse outcomes’ [11].”
Improvement in Usual Gait Speed Predicts Better Survival in Older Adults (2007, background): “’’(21) It may indicate a kind of resilience, or an ability to improve or recover from a prior stressful event.(22,23) Improved gait speed over time might also indicate improved physiological health due to medical interventions or change in health behaviors such as physical exercise.”
The I.A.N.A. task force on frailty assessment of older people in clinical practice (2008, neutral): “(14) c) Canadian initiative on Frailty and Aging.”
Frailty Syndrome: A Transitional State in a Dynamic Process (2009, background): “Recent research efforts have helped to better define the clinical and physiological characteristics of frailty and to highlight the vulnerability of frail, older adults to poor health outcomes [”
A comparison of two approaches to measuring frailty in elderly people. (2007, background): “The phenotypic definition allows for mechanisms to be explored, by testing for shared elements in the pathophysiology of each item (24).”