Spleen Tyrosine Kinase Syk Is Necessary for E-Selectin-Induced αLβ2 Integrin-Mediated Rolling on Intercellular Adhesion Molecule-1

By Alexander Zarbock, C. Lowell, Klaus Ley. 2007

291 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy, Oncology

View Paper: https://www.semanticscholar.org/paper/00f1144a7e8b3b3e86db33bdc4d50a3047dac1fa

Citations in the corpus

• Mammalian glycosylation in immunity (2008, unknown): “Once engaged by their cognate glycan ligands, the selectins recruit tyrosine kinases, such as Fyn and spleen tyrosine kinase (Syk), to their cytoplasmic domains, thereby inducing intracellular tyrosine phosphorylation, activating mitogen-activated protein kinases and promoting integrin activatio”