Thrombotic thrombocytopenic purpura associated with clopidogrel.
By C. Bennett, J. Connors, J. Carwile, J. Moake, W. Bell, S. Tarantolo, L. Mccarthy, R. Sarode, Amy J. Hatfield, M. Feldman and 3 more. New England Journal of Medicine, 2000
636 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Genetics, Immunology
View Paper: https://www.semanticscholar.org/paper/008be9fcec79ef407e2086ccb6ad25a2f45eff82
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Citations in the corpus
- Identification of the platelet ADP receptor targeted by antithrombotic drugs (2001, background): “However, these drugs work through a mechanism of covalent protein modification, which might underlie their recent association with the syndrome thrombotic thrombocytopenic purpur”
- ACC/AHA guidelines for the management of patients with unstable angina and non–st-segment elevation myocardial infarction: A report of the american college of cardiology/ american heart association task force on practice guidelines (committee on the management of patients with unstable angina) (2000, background): “was required in 10 of the patients, and 1 patient died (191).”
- Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura (2001, background): “has been shown to be decreased in the plasma of TTP patients, either on the basis of a constitutional deficiency in congenital cases or the presence of an autoantibody inhibitor in most sporadic adult-onset case”
- ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. (2003, neutral): “Response, % (proportion) 89 (16/18) 71 (5/7) 39 (9/23) 60 (56/94) Exacerbation, % (proportion)‡ 56 (9/16) 80 (4/5) 33 (3/9) 11 (6/56) Median no. of plasma exchange (minimum, maximum)§ 21 (5, 74) 45 (2, 68) 18 (8, 59) 10 (0, 37 ) TTP-HUS-associated death, % (proportion) 17 (3/18) 14 (1/7) 61 (14/23)”
- Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. (2014, background): “Neutropenia did not occur more frequently among patients assigned to clopidogrel than among those given aspirin or placebo in published trials,(443,533) but a few cases of thrombotic thrombocytopenic purpura have been described.(540) Recently, evidence has emerged that proton pump inhibitors (PPIs),”