A more efficient method to generate integration-free human iPS cells

By K. Okita, Y. Matsumura, Yoshiko Sato, Aki Okada, A. Morizane, S. Okamoto, Hyenjong Hong, M. Nakagawa, K. Tanabe, Ken-Ichi Tezuka and 6 more. Nature Methods, 2011

1,979 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/005b8ea7629740f6419668162c243c902e36c58e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. S. Yamanaka
2. K. Okita
3. Kazutoshi Takahashi
4. T. Aoi
5. K. Hochedlinger
6. Mark Gerstein
7. M. Stadtfeld
8. R. Jaenisch

In Physiology

1. Kazutoshi Takahashi
2. S. Yamanaka
3. K. Okita
4. W. Klein

Citations in the corpus

• Targeting RNA foci in iPSC-derived motor neurons from ALS patients with C9ORF72 repeat expansion (2013, methodology): “Reprogramming of the lines was performed with pCXLE-hUL, pCXLE-hSK, and pCXLE-hOCT3/4-shp53-F vectors [Addgene, adapted from previously published protocols (20)].”
• FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders (2015, positive): “Induced Pluripotent Stem Cells For each proband and first degree unaffected family members, iPSC were produced using the classical retroviral approach or by a viral-free episomal reprogramming method (Okita et al., 2011).”
• Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013, background): “iPSC generation and cortical-neuronal differentiation Dermal fibroblasts were reprogrammed by episomal vectors (Okita et al., 2011).”