De novo genome assembly: what every biologist should know

By Monya Baker. Nature Methods, 2012

232 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Contiguous and accurate de novo assembly of metazoan genomes with modest long read coverage (2015, unknown): “For example, because high quality genome assembly relies upon long sequencing reads to bridge repetitive genomic regions(6,8,16,17) and high coverage to circumvent read errors (4,7,13), the”
Improvements to PATRIC, the all-bacterial Bioinformatics Database and Analysis Resource Center (2016, background): “A variety of command-line programs exist for assembling sequence reads into contigs, but these often require programming skills and considerable expertise to use effectively (8).”
Applications of next-generation sequencing to the study of biological invasions (2015, background): “Excellent reviews are available on de novo genome assembly (Baker, 2012) and use of ge- nome sequencing in non-model organisms (Ellegren, 2014).”
Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species (2013, background): “Several recent commentaries that address many of the problems inherent in de novo genome assembly [14,18-22], have also identified a range of solutions to help tackle these issues.”