Kristen E. Mengwasser
Proceedings of the National Academy of Sciences of the United States of America · 2008–2013
A researcher in the Science corpus: 2 papers; trusts 1 researcher and is trusted by 0 researchers here, as inferred from the citation graph.
Whom Kristen E. Mengwasser trusts overall
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Who trusts Kristen E. Mengwasser overall
Papers from Kristen E. Mengwasser's perspective
Ordered by how strongly the researchers Kristen E. Mengwasser trusts endorse each paper. Same corpus, a different order for every researcher.
- Refinement of macromolecular structures by the maximum-likelihood method.
- Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor* (Journal of Biological Chemistry)
- An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. (Cell)
- Pushing the boundaries of molecular replacement with maximum likelihood.
- Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. (Cancer Cell)
- Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. (Proceedings of the National Academy of Sciences of the United States of America)
- Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. (Cancer Cell)
- Analysis of Epidermal Growth Factor Receptor Gene Mutation in Patients with Non–Small Cell Lung Cancer and Acquired Resistance to Gefitinib (Clinical Cancer Research)
- BioGRID: a general repository for interaction datasets
- A method and server for predicting damaging missense mutations
Their papers
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP (2008) — 2,013 citations
- Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns to Shape the Cancer Genome (2013) — 779 citations