George M. Burslem
Molecular Biology · 2017–2020
A researcher in the Science corpus: 2 papers; trusts 2 researchers and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 36 citations into it
- Oncology — 7 citations into it
Whom George M. Burslem trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Papers from George M. Burslem's perspective
Ordered by how strongly the researchers George M. Burslem trusts endorse each paper. Same corpus, a different order for every researcher.
- The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins (Science)
- Catalytic in vivo protein knockdown by small-molecule PROTACs (Nature Chemical Biology)
- Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. (Chemistry and Biology)
- Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation (Proceedings of the National Academy of Sciences of the United States of America)
- Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells (Science)
- Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
- A small molecule–kinase interaction map for clinical kinase inhibitors (Nature Biotechnology)
- A quantitative analysis of kinase inhibitor selectivity (Nature Biotechnology)
- Selective Target Protein Degradation via Phthalimide Conjugation (Science)
- Faculty Opinions recommendation of Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
Their papers
- Lessons in PROTAC design from selective degradation with a promiscuous warhead (2017) — 738 citations
- Proteolysis Targeting Chimeras as Therapeutics and Tools for Biological Discovery (2020) — 836 citations