J. D. de Bono
Oncology · 2008–2021
A researcher in the Science corpus: 19 papers; trusts 4 researchers and is trusted by 1 researcher here, as inferred from the citation graph.
Subfields
- Oncology — 90 citations into it
- Molecular Biology — 77 citations into it
Whom J. D. de Bono trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts J. D. de Bono overall
Papers from J. D. de Bono's perspective
Ordered by how strongly the researchers J. D. de Bono trusts endorse each paper. Same corpus, a different order for every researcher.
- Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase (Nature)
- Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study. (The Lancet Oncology)
- High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs (Proceedings of the National Academy of Sciences of the United States of America)
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer (New England Journal of Medicine)
- Functional interaction between PARP‐1 and PARP‐2 in chromosome stability and embryonic development in mouse (EMBO Journal)
- 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks (Cell)
- DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs (Chemistry and Biology)
- DNA repair dysregulation from cancer driver to therapeutic target (Nature Reviews. Cancer)
- Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors (EMBO Molecular Medicine)
- Repair Pathway Choices and Consequences at the Double-Strand Break (Trends in Cell Biology)
Their papers
- Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. (2009) — 3,580 citations
- Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. (2010) — 991 citations
- Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer (2021) — 1,884 citations
- Olaparib for Metastatic Castration-Resistant Prostate Cancer. (2020) — 1,824 citations
- Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer. (2020) — 617 citations
- Patient-derived organoids model treatment response of metastatic gastrointestinal cancers (2018) — 1,767 citations
- Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy (2017) — 1,576 citations
- Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. (2016) — 1,381 citations
- Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action (2016) — 665 citations
- Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study. (2015) — 1,271 citations
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer (2015) — 1,991 citations
- Enzalutamide in Metastatic Prostate Cancer before Chemotherapy (2014) — 2,782 citations
- Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. (2012) — 1,346 citations
- Randomized Phase 3 Trial of Abiraterone Acetate in Men with Metastatic Castration-Resistant Prostate Cancer and No Prior Chemotherapy (2012) — 902 citations
- Increased survival with enzalutamide in prostate cancer after chemotherapy. (2012) — 4,361 citations
- Abiraterone and Increased Survival in Metastatic Prostate Cancer (2011) — 4,290 citations
- Circulating Tumor Cell Number as a Prognostic Marker in Progressive Castration-Resistant Prostate Cancer: Use in Clinical Practice and Clinical Trials (2009) — 598 citations
- Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer (2008) — 1,983 citations
- Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. (2008) — 886 citations