Representation of elderly persons and women in published randomized trials of acute coronary syndromes.

By Patrick Y. Lee, K. Alexander, B. Hammill, S. Pasquali, E. Peterson. Journal of the American Medical Association (JAMA), 2001

885 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/ff94a19699cfb0f4d222e003edb8ee7ef5f66dd9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

A. Battler
D. Hasdai
Anselm K. Gitt
E. Boersma
S. Behar
L. Wallentin
M. Simoons
N. Danchin

Citations in the corpus

Multimorbidity (2022, methodology): “Chan School of Public Health (BLSCHP-1902), Bloomberg Philanthropies (via University of North Carolina at Chapel Hill School of Public Health), FONDECYT via CIENCIACTIVA/CONCYTEC, British Council, British Embassy and the NewtonPaulet Fund (223-2018, 224-2018), DFID/ MRC/Wellcome Global Health Trials”
Aging Biology and Geriatric Clinical Pharmacology (2004, background): “…myocardial infarctions are older than 75 years, an overview of 593 randomized trials of interventions in acute coronary syndromes published since 1966 showed that only 2% of all patients in studies between 1966 and 1990 were older than 75 years, rising to 9% over the next decade (Lee et al., 2001).”
A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin; the Euro Heart Survey of Acute Coronary Syndromes (Euro Heart Survey ACS). (2002, background): “Clinical trials clearly enrol a select patient population with a better risk profile([9,10]).”
Women and men with stable coronary artery disease have similar clinical outcomes: insights from the international prospective CLARIFY registry (2012, neutral): “The data from clinical trials related to women should be interpreted carefully since they are often performed in highly selected populations with under-representation of women.(23) Registry studies, particularly when performed nationwide,(24,25) provide more representative data regarding gender diff”