Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

By Liping Zhao, Feng Zhang, Xiaoying Ding, Guojun Wu, Y. Lam, Xuejiao Wang, Huaqing Fu, Xinhe Xue, Chunhua Lu, Jilin Ma and 23 more. Science, 2018

1,984 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/ff711bb96b580fd91630e757b2f17c692164eac6

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Citations in the corpus

Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health (2020, methodology): “Modulation of the human gut microbiome with dietary interventions has been extensively studied, mainly focusing on the supplementation of NDCs. 74 78 79 However, the impact of dietary components on the stability and resilience of the gut ecosystem has been barely addressed.”
The gut microbiome: Relationships with disease and opportunities for therapy (2018, background): “Recently, a diet rich in fiber was shown to significantly improve glucose control and promote a healthier metabolic profile in T2DM patients (Zhao et al., 2018).”
Gut Microbiota and Immune System Interactions (2020, background): “SCFAs are fatty acids with fewer than six carbon atoms, mainly consisting of acetate, propionate, and butyrate [1,9].”
Gut microbiota-derived metabolites as central regulators in metabolic disorders (2020, background): “The amount of SCFA-producing bacteria and SCFAs is reduced in faecal samples of dysmetabolic mice 62 and in humans with obesity and diabetes.”
Short chain fatty acids in human gut and metabolic health. (2020, positive): “A study by Zhao et al. (2018) showed that a diet rich in complex fibre mixtures for 12 weeks decreased haemoglobin A1c levels and fasting blood glucose and improved glucose tolerance by approximately 20% in T2DM individuals.”
Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration (2019, background): “However, these may draw a pre-emptory conclusion with limited dietary and faecal time-points investigating one dietary shift [108].”
Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis (2022, methodology): “SCFA supplementation in patients with T2DM increased the abundance of butyrate-producing bacteria and increased GLP-1 and hemoglobin A1c levels [101].”