Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

By H. Duboc, Sylvie Rajca, D. Rainteau, David Benarous, M. Maubert, Elodie Quervain, G. Thomas, V. Barbu, L. Humbert, G. Despras and 14 more. Gut, 2012

837 citations recorded by the source corpus.

Subfields: Hepatology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/ff5adfc098173e214d4f72ad0185a71c8e9777a8

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In Molecular Biology

1. Li Zhan
2. Tianzhi Wu
3. Sara Vieira-Silva
4. Jeroen Raes
5. Wenli Tang
6. Zijing Xie
7. Shuangbin Xu
8. Xiao Luo

Citations in the corpus

• How informative is the mouse for human gut microbiota research? (2015, background): “…et al., 2011; Sokol et al., 2009; Willing et al., 2009), as well as of Clostridium coccoides and Bifidobacterium (Sokol et al., 2009), and an increase in abundance of Enterobacteriaceae (such as E. coli) (Duboc et al., 2013; Joossens et al., 2011; Willing et al., 2009; Willing et al., 2010).”
• Using clusterProfiler to characterize multiomics data (2024, positive): “Perform enrichment analysis of differential metabolites cpd_enrich_result - compareCluster(geneClusters = de_cpd, fun = "enrichKEGG", organism = "cpd") To conduct an enrichment analysis using the KEGG Compound database (CPD), which aids in characterizing biological processes relevant to the differe”
• Current understanding of dysbiosis in disease in human and animal models (2016, background): “It has been found that patients with IBD exhibit the characteristic dysbiosis pattern and defective BA metabolism in the intestine, particularly during an IBD flare.(14) Alterations in the gut microbiota have shown to affect BA metabolism because the microbiota and its associated metabolites mediate”