Global dynamics of proteins: bridging between structure and function.

588 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Revealing evolutionary constraints on proteins through sequence analysis (2018, methodology): “Every pair of carbons within a cutoff distance dc is then connected with a harmonic spring [11].”
Designing allostery-inspired response in mechanical networks (2016, background): “In fact, folded proteins have long been modeled as elastic networks (13), and the response to localized forces in the resulting networks has been studied (14).”
Design of Elastic Networks with Evolutionary Optimized Long-Range Communication as Mechanical Models of Allosteric Proteins (2017, background): “Despite their approximate nature, such simpliﬁed descriptions have signiﬁcantly contributed to understanding the mechanistic underpinnings of allostery in proteins (27,28).”
Allostery in Its Many Disguises: From Theory to Applications (2019, background): “As seen above, such soft modes may be readily described by coarsegrained models like those Bahar et al. (2010) and others (Hawkins and McLeish, 2004; Zhu et al., 2011).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “Insight into the actual kinetics of the motor can be gained by carrying normal mode analysis (NMA) which yields the spectrum of collective modes of the elastic network [393, 394, 395, 396, 397, 398, 399, 400].”