Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.

By S. Bunyavanich, Anh N. Do, A. Vicencio. Journal of the American Medical Association (JAMA), 2020

770 citations recorded by the source corpus.

This study compares angiotensin-converting enzyme 2 (ACE2) gene expression, which has been associated with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/ff19b70f9296f350dab87c5fc14c90cf884a7390

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. É. B. Rangel
2. E. B. Casaro
3. Stephany Beyerstedt

Citations in the corpus

• Predictors of COVID-19 severity: A literature review (2020, background): “enzyme angiotensin-converting enzyme 2 (ACE2) receptors in their nasal epithelia.(130) Because ACE2 is a functional receptor of SARSCoV-2,(131,132) it is possible that lower expression of ACE2 in nasal epi-”
• COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection (2021, positive): “in an age-dependent manner and may explain, at least in part, the reason why the younger ones have lower incidence of COVID-19, since they exhibited the lowest nasal gene expression of ACE2 [39].”
• Multisystem Inflammatory Syndrome in U.S. Children and Adolescents (2020, neutral): “(%)** 21/62 (34) 15/55 (27) 9/36 (25) 45/153 (29)”