Screening of isolated potential probiotic lactic acid bacteria for cholesterol lowering property and bile salt hydrolase activity

By M. Shehata, S. A. Sohaimy, M. El-Sahn, M. Youssef. 2016

293 citations recorded by the source corpus.

Abstract A total of 142 isolates of lactic acid bacteria (LAB) were isolated from dairy and non-dairy sources. The LAB isolates were screened for antimicrobial activity. Out of 142 isolates only 68 isolates exhibited antimicrobial activity. Among these isolates, nine showed wide spectrum antimicrobial activity as well as good bile salt, acid and phenol tolerance. Seven isolates of the latter ones showed more than 20% cholesterol reduction and an observed bile salt hydrolase (BSH) activity. The promising isolates were identified using phenotypic, biochemical and genetic methods.

Subfields: Biotechnology, Food Science, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/febf4ecb341137ccfdbd3f38b1ed7956f4ae51c6