Emerging roles for platelets as immune and inflammatory cells.

By C. Morrell, Angela A. Aggrey, Lesley M. Chapman, Kristina L. Modjeski. Blood, 2014

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Circulating Platelets as Mediators of Immunity, Inflammation and Thrombosis (2018, background): “Notably, platelets contain the mRNA transcripts for all TLR1 to TLR10 (Toll-like receptors).(4,51,52) TLRs are”
Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020 (2020, background): “Following platelet activation, the platelet α -, dense, lysosomal, and T-granules undergo regulated exocytosis and release their contents into the extracellular environment (Figure 2) [99,100].”
Platelets at the interface of thrombosis, inflammation, and cancer. (2015, background): “Therefore, it comes as no surprise that platelets so frequently pervade immunologic functions.(3) Although not strictly appointed within the inflammatory pathway, the platelet can be viewed as an extension of the cellular immune system.”