Commercial production of astaxanthin from Haematococcus pluvialis using 25,000-liter outdoor photobioreactors

By M. Olaizola. Journal of Applied Phycology, 2000

370 citations recorded by the source corpus.

Subfields: Environmental Chemistry, Oceanography, Renewable Energy, Sustainability and the Environment

View Paper: https://www.semanticscholar.org/paper/fd17d0b90f55a00e9445d423bbc1224b7a248997

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Citations in the corpus

Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review (2014, neutral): “4 [24]”
Interplay between photochemical activities and pigment composition in an outdoor culture of Haematococcus pluvialis during the shift from the green to red stage (2003, background): “Notwithstanding these limitations H. pluvialis is nowadays the main candidate for the production of astaxathin for commercial purpose (Olaizola 2000).”
Comparison of Microalgae Cultivation in Photobioreactor, Open Raceway Pond, and a Two-Stage Hybrid System (2016, background): “Two-phase hybrid cultivation systems have been proposed as an advantageous microalgae cultivation system, as they are able to essentially separate biomass growth from the lipid accumulation phase (Olaizola, 2000; Schenk et al., 2008; Su et al., 2011).”
Scaling up microalgal cultures to commercial scale (2017, background): “duction is less than that (Belay, 1997; Weissman et al., 1989; Olaizola, 2000; Jiménez et al., 2003), although high productivities of up to about 50 g m day can be achieved in small indoor cultures under optimal conditions, and productivities > 30 g m day in small (1–5 m(2)) raceway ponds outdoors”
Microzooplanktonic grazers – A potentially devastating threat to the commercial success of microalgal mass culture (2017, background): “63 Other microalgae cultivated under less harsh environmental conditions, such as Haematococcus pluvialis 64 for astaxanthin production, are more susceptible to being outcompeted by other microalgae and are most 65 commonly grown in more enclosed photobioreactor systems [10, 11].”
Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions. (2013, background): “In the first stage vegetative cells are cultivated under near optimal growth condition, while in the second stage the cells are subjected to a combination of environmental and nutrient stresses, such as nitrate and phosphate starvation or increasing temperature and light, or by increasing salinity o”
Algal transgenics and biotechnology (2007, background): “In the 1990s in the USA and India, several plants started with large-scale production of Haematococcus pluvialis as a source of the carotenoid astaxanthin, which is used in pharmaceuticals, nutraceuticals, agriculture, and animal nutrition (Olaizola 2000; Spolaore et al. 2006).”
Outdoor cultivation of microalgae for carotenoid production: current state and perspectives (2007, background): “5–3% of the dry biomass after this reddening phase, although some authors claim even higher values (Guerin et al. 2003; Olaizola 2000).”
Astaxanthin-Producing Green Microalga Haematococcus pluvialis: From Single Cell to High Value Commercial Products (2016, background): “Usually haematocysts are separated from the water through passive settling and subsequently concentrated with centrifugation (Lorenz and Cysewski, 2000; Olaizola, 2000; Li et al., 2011; Han et al., 2013; Pérez-López et al., 2014).”