Genotoxicity testing of quizalofop-P-ethyl herbicide using the Allium cepa anaphase-telophase chromosome aberration assay
By Y. Mustafa, Evrim Suna Arikan. 2008
122 citations recorded by the source corpus.
Abstract Cytogenetic effects of phenoxy herbicide viz. quizalofop-P-ethyl (QPE, ethyl (R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy] propionate) were evaluated in the root meristem cells of Allium cepa. In the Allium root growth test, the effective concentration (EC50) value was determined as approximately 1.5 ppm. Cytological experiments were carried out using QPE concentrations of 0.75 (EC50/2), 1.5 (EC50) and 3 ppm (EC50x2) at 24, 48, 72, and 96 h, with a control for each combination. Mitotic index decreased with increasing the herbicide concentration at each exposure time. In anaphase-telophase cells, the total percentages of stickiness, bridges, vagrant chromosomes, c-anaphase, multipolarity, and fragments according to total cells with chromosome aberrations were calculated as 38.57, 28.42, 16.67, 14.10, 1.60, and 0.64%, respectively. The total chromosome aberrations increased with an increasing the QPE concentration. Micronucleated cells were observed at interphase. The frequency of the micronucleus was markedly higher at 3 ppm compared to other test concentrations.
Subfields: Cancer Research, Plant Science, Pollution
View Paper: https://www.semanticscholar.org/paper/fcad618d3ca18bf6a9c700d2b8478a1796df66d1
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
In Plant Science
In Pollution
Citations in the corpus
- Determination of genotoxic effects of chlorfenvinphos and fenbuconazole in Allium cepa root cells by mitotic activity, chromosome aberration, DNA content, and comet assay (2012, background): “cepa species has showed to be an efficient species for such studies, mainly when it is used for assays of chromosome aberrations and for genetic tests [12–15].”
- Allium Cepa Root Chromosomal Aberration Assay: A Review (2013, unknown): “Quizalofop-P-ethyl Herbicide stickiness, bridge/s, vagrant/s, canaphase, multipolarity, micronuclei [28]”