A review of the multiple actions of melatonin on the immune system

By A. Carrillo-Vico, J. Guerrero, P. Lardone, R. Reiter. Endocrine, 2005

658 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems

View Paper: https://www.semanticscholar.org/paper/fca5c297cf026687dfc1fc8fb4da0912d00ccf4b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrine and Autonomic Systems

Citations in the corpus

Melatonin: Buffering the Immune System (2013, background): “Original studies from the last few decades have also identified de novo synthesis of melatonin by the immune system, which was reviewed in [14].”
Melatonin membrane receptors in peripheral tissues: Distribution and functions (2012, positive): “There is a reported direct correlation between melatonin levels at its peak during darkness, and the maximal immune cell proliferation (Carrillo-Vico et al., 2005).”
Melatonin: a multitasking molecule. (2010, background): “Among other possible functions, these binding sites are involved in melatonin’s inhibition of inflammation (Carrillo-Vico et al., 2005) and possibly also in the stimulation of antioxidative enzymes (TomasZapico and Coto-Montes, 2005).”
Physiological roles of tryptophan in teleosts: current knowledge and perspectives for future studies (2019, background): “…above, melatonin is synthesized through 5HT and is involved in the 698 regulation of several important physiological and behavioural functions, including the 699 mammalian circadian rhythm, patterns of sleep, thermoregulation, reproduction and also 700 immune function (Carrillo-Vico et al., 2005).”
Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions (2014, background): “ROR/RZR has been proposed to work in coordination with the plasma membrane receptors MT1/MT2 to regulate gene expression [14].”
A review of the molecular aspects of melatonin’s anti‐inflammatory actions: recent insights and new perspectives (2013, background): “Specific membrane and nuclear receptors have been described for melatonin in different tissues from many different species [21].”
Melatonin: Pharmacology, Functions and Therapeutic Benefits (2017, background): “Concerning the role of melatonin in immune regulation, melatonin has direct immuno-enhancement effects in animals and humans [75, 76].”
Melatonin as a natural ally against oxidative stress: a physicochemical examination (2011, background): “For example, it is now accepted that it has immuneenhancing [13] and anti-inflammatory [14, 15] properties, that it exerts homeostatic roles in the mitochondrion [16– 18], and that it inhibits cancer progression [19–21].”
The dark side of light at night: physiological, epidemiological, and ecological consequences (2007, background): “provide an excellent review of the effects of melatonin on the immune system [59].”
Melatonin--a pleiotropic, orchestrating regulator molecule. (2011, background): “Relatively high levels were detected especially in T- and Blymphocytes, neutrophils and monocytes (Garcı́a-Mauriño et al., 1997, 1998; Carlberg, 2000; Guerrero et al., 2000a; Guerrero and Reiter, 2002; Carrillo-Vico et al., 2005a, 2006).”