Targeting bromodomains: epigenetic readers of lysine acetylation

By P. Filippakopoulos, S. Knapp. Nature reviews. Drug discovery, 2014

1,195 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/fc88d3901f9479e5ddb63fd5ade83dcd74df7cba

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1. Kanak Raina
2. Jing Lu
3. Y. Qian
4. M. Altieri
5. D. Gordon
6. AnnMarie K. Rossi
7. Kam W. Siu
8. Jing Wang

Citations in the corpus

• PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer (2016, methodology): “To meet our twin goals of developing a highly potent BET protein degrader that also possesses a pharmacokinetic (PK) profile favorable for in vivo testing, we used the triazolo-diazepine acetamide BET-binding moiety derived from BET inhibitors in clinical development (29).”