Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics
By Joohee Kim, Minji Kim, Mi-Sun Lee, Kukjoo Kim, Sangyoon Ji, Yun‐Tae Kim, Jihun Park, Kyungmin Na, Kwi-Hyun Bae, Hong Kyun Kim and 3 more. Nature Communications, 2017
826 citations recorded by the source corpus.
Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on an actual ocular contact lens. It was also designed to monitor glucose within tears, as well as intraocular pressure using the resistance and capacitance of the electronic device. Furthermore, in-vivo and in-vitro tests using a live rabbit and bovine eyeball demonstrated its reliable operation. Our developed contact lens sensor can measure the glucose level in tear fluid and intraocular pressure simultaneously but yet independently based on different electrical responses. Wearable electronics have been utilized for a number of applications including for ocular use, although their use has been limited to a single function. Here, the authors developed a multifunctional contact lens with wireless electronics for measurement of glucose and intraocular pressure.
Subfields: Biomedical Engineering, Electrical and Electronic Engineering, Human-Computer Interaction
View Paper: https://www.semanticscholar.org/paper/fbaa1f563520fe109c7bd913f7b8e9be76fd1ec5
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Citations in the corpus
- The Emergence of AI-Based Wearable Sensors for Digital Health Technology: A Review (2023, methodology): “In addition, tears were used for monitoring human eye intraocular pressure as an indicator for glaucoma, which can cause blindness, using soft contact lenses for the wireless detection of both glucose and intraocular pressure [151].”
- Flexible Sensors—From Materials to Applications (2019, methodology): “However, there are several other examples of flexible substrates suitable for sensor applications reported in literature, including PU [96,316,317], PLA [293], polysulfone (PSU) [318], polyetheretherketone (PEEK) [319], polycarbonate (PC) [79], parylene [47], polyvinyl alcohol (PVA) [12], polyarylat”