Clearance of apoptotic cells: getting rid of the corpses.

By K. Lauber, S. Blumenthal, M. Waibel, S. Wesselborg. Molecules and Cells, 2004

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Apoptosis and cancer: mutations within caspase genes (2009, background): “rapidly phagocytosed by the macrophages with the result that the cell disappears without any inflammatory phenomena.(7) Apoptosis induction might be achieved in several ways—for example, by promoting the expression of pro-apoptotic factors while reducing the expression of antiapoptotic factors only ”
Hallmarks of neurodegenerative diseases. (2023, unknown): “257 These examples highlight the close interconnection between inﬂammation and other NDD hallmarks.”
Apoptotic cells promote their own clearance and immune tolerance through activation of LXR (2009, unknown): “In contrast to other types of phagocytosis, such as bacterial or necrotic cell uptake, scavenging of apoptotic cells is immunologically silent (Lauber et al., 2004).”
Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. (2008, unknown): “To prevent the diffusion of damaging degradation products into the surrounding tissue it is essential that the dying neurons are quickly recognized and phagocytosed (Lauber et al., 2004; Platt et al., 1998).”