Cyclodextrin-based supramolecular systems for drug delivery: Recent progress and future perspective
By Jianxiang Zhang, P. Ma. Advanced Drug Delivery Reviews, 2013
762 citations recorded by the source corpus.
The excellent biocompatibility and unique inclusion capability as well as powerful functionalization capacity of cyclodextrins and their derivatives make them especially attractive for engineering novel functional materials for biomedical applications. There has been increasing interest recently to fabricate supramolecular systems for drug and gene delivery based on cyclodextrin materials. This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery. First, we introduce cyclodextrin materials utilized for self-assembly. The fabrication technologies of supramolecular systems including nanoplatforms and hydrogels as well as their applications in nanomedicine and pharmaceutical sciences are then highlighted. At the end, the future directions of this field are discussed.
Subfields: Biomaterials, Organic Chemistry, Pharmaceutical Science
View Paper: https://www.semanticscholar.org/paper/fb4a12e29283485e22af54389998befd0d5aca87
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In Biomaterials
In Organic Chemistry
Citations in the corpus
- Nanocomposite Hydrogels: 3D Polymer-Nanoparticle Synergies for On-Demand Drug Delivery. (2015, background): “Cyclodextrins (CDs) have also been widely studied as drug delivery systems.(55) As a result of their molecular structure and shape, they are usually used to complex poorly water-soluble drugs, increasing their aqueous solubility.”