Identification Of Two Distinct Inactive Conformations Of The Beta-2 Adrenergic Receptor Reconciles Structural And Biochemical Observations

By Ron O. Dror, Daniel H Arlow, David W. Borhani, Morten Ø. Jensen, David E. Shaw. 2009

93 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/fa32bad1760d6eb1004dc5b1c4e9a689b35d98eb

Citations in the corpus

• Structural insights into the dynamic process of β2-adrenergic receptor signaling (2015, unknown): “Although crystal structures of antagonist-bound b2AR consistently show a broken ionic lock, molecular dynamics simulations indicate that the receptor transitions frequently between the two conformations (Dror et al., 2009).”