The Evolution of Genetic Architecture

By Thomas F. Hansen. 2006

385 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/fa288d678eadea400306a05b580ba8eb5f46c2fe

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In Genetics

Citations in the corpus

Evolution, the Extended Synthesis (2010, background): “Concepts such as evolvability (Wagner and Altenberg 1996; R. L. Carroll 2002; Love 2003b; Wagner 2005; Hansen 2006; Hendrikse et al. 2007; Colegrave and Collins 2008; Pigliucci 2008), for instance, did not exist in the literature before the early 1990s; phenotypic plasticity (West-Eberhard 1989;…”
The genomics of local adaptation in trees: are we out of the woods yet? (2017, background): “…uncertainty regarding the exact number of loci underlying many adaptive traits, the effect size distribution of these loci, and how the number of underlying loci and effect distribution may change under various evolutionary regimes (Orr 2001; Slate 2005; Hansen 2006; Mackay et al. 2009).”
Measuring and comparing evolvability and constraint in multivariate characters (2008, background): “Often it is defined as a property of the genotype–phenotype map and involves structural characteristics such as mutability, variability, autonomy, modularity, coordination and continuity (Wagner & Altenberg, 1996; Hansen, 2006).”
Intralocus Sexual Conflict (2009, background): “The evolution and stability of the G matrix, which summarizes the pattern of segregating genetic variation, has not been investigated for genetic systems that include epistasis and sex-specific selection (Hansen 2006; Arnold et al. 2008).”
Statistical genetics and evolution of quantitative traits (2011, background): “While the map itself is unambiguous, several different ways of parametrizing fitness landscapes with alleles and groups of alleles have been proposed (Barton and Turelli, 1991; Weinberger, 1991; Hansen and Wagner, 2001; Hansen, 2006).”
Constraints Evolve: Context Dependency of Gene Effects Allows Evolution of Pleiotropy (2015, background): “Alternative alleles at a locus can themselves differ in the number of traits they affect (see Hansen 2006).”
Developmental Dynamics and G-Matrices: Can Morphometric Spaces be Used to Model Phenotypic Evolution? (2008, background): “…underlying genetic, developmental, or environmental factors, though the additive phenotypic effects of those factors are described by G and so influence the direction and magnitude of evolutionary changes predicted by these equations (Maynard Smith et al. 1985; Steppan et al. 2002; Hansen 2006).”
Heritability is not Evolvability (2011, background): “From the Lande equation we can then infer that e = VA, where VA is the additive genetic variance.”
Neuronal boost to evolutionary dynamics (2015, background): “neuronal states, in an equivalent way to development decoding the genetic information into a trait, which is one of the fundamental aspects of evolvability [39–41].”
Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions (2016, neutral): “…rates among those regions (i.e., their relative physical positions on chromosomes), the distribution of ﬁ tness effects, and the degree of redundancy, as well as patterns of dominance, pleiotropy (multiple traits affected by the same gene), and epistasis (gene interactions; Hansen 2006).”