Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest.

By K. Sunde, M. Pytte, D. Jacobsen, A. Mangschau, L. P. Jensen, Christian Smedsrud, T. Draegni, P. Steen. Resuscitation, 2007

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European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators (2010, background): “[37] [38] [39] Therapeutic hypothermia is now an established therapy that greatly contributes to improved survival with good neurological outcome.”
Part 8: Post–Cardiac Arrest Care (2015, positive): “MAP greater than 65 mm Hg increased survival to hospital discharge, with a favorable neurologic outcome at 1 year.(37) Another bundle with a goal MAP greater than 65 mm Hg within 6 hours found no change in in-hospital mortality or functional recovery at hospital discharge.”
European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. (2015, methodology): “Bilateral absence of pupillary light reflex at 72 h from ROSC redicts poor outcome with close to 0% FPR, both in TTMreated and in non-TTM-treated patients (FPR 1 [0–3] and 0 [0–8], n 95 (2015) 202–222”
Intensive care unit mortality after cardiac arrest: the relative contribution of shock and brain injury in a large cohort (2013, background): “However, we confirmed that post-CA shock was not associated with a higher risk of death on multivariate analysis, even for patients treated with TH [29–33, 35].”