Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients

By T. Bjarnsholt, P. Ø. Jensen, M. Fiandaca, Jette Pedersen, C. Hansen, Claus B. Andersen, T. Pressler, M. Givskov, Niels Høiby. Pediatric Pulmonology, 2009

791 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/518d0c41be89a85ea59a77b881418f891482e3ae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. T. Bjarnsholt
2. Niels Høiby
3. M. Givskov
4. S. Gellatly
5. Søren Molin
6. O. Ciofu
7. G. Donelli
8. L. Hall-Stoodley

In Pulmonary and Respiratory Medicine

1. Robert E. W. Hancock
2. S. Gellatly
3. T. Bjarnsholt

Citations in the corpus

• Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action (2017, background): “increase their resistance against the conventional antibiotics by around 1000-fold.(2,6,15-20) Some other factors may also account for this antimicrobial tolerance.”
• Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections (2016, background): “aeruginosa protection from antibiotics and host responses [14].”
• Antibiotic resistance of bacterial biofilms. (2010, background): “biofilms may play a role in the tolerance of biofilms to aminoglycosides (2).”
• ESCMID guideline for the diagnosis and treatment of biofilm infections 2014. (2015, methodology): “Lung infections (CF) Light microscopy ~4–8 μm [197] Light microscopy ~5–100 μm [198] FISH ~5–100 μm [8] FISH ~5–50 μm [199] Chronic wounds FISH ~5–200 μm [40] FISH ~5–100 μm [9] Light and electron microscopy ~35–55 μm [39]”
• Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. (2013, background): “aeruginosa in the lung sputum of chronically infected patients with CF have been observed and resemble mucoid colonies grown in the laboratory (Bjarnsholt et al., 2009).”
• Critical review on biofilm methods (2017, background): “, 2003) and more recent applications mostly focus on clinical biofilms (Bjarnsholt et al., 2009; Freiberg et al., 2014; Kragh et al., 2014; Malic et al., 2009).”