Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease.
By M. Klempner, Linden T. Hu, Janine Evans, Christopher H. Schmid, G. M. Johnson, Richard P. Trevino, Delona Norton, L. Levy, D. Wall, J. McCall and 2 more. New England Journal of Medicine, 2001
725 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology, Parasitology
View Paper: https://www.semanticscholar.org/paper/f8b1650123a84926844e647d0fb4d0aa29a6929e
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- G. Stanek
- F. Strle
- Klaus-Peter Hunfeld
- G. Wormser
- B. Jaulhac
- R. Kaiser
- A. Krause
- Wolfgang Kristoferitsch
Citations in the corpus
- The emergence of Lyme disease. (2004, background): “the groups in the percentage of patients who said that their symptoms had improved, gotten worse, or stayed the same (81).”
- The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. (2006, neutral): “burgdorferi infection can exist despite recommended treatment courses of antibiotics (tables 2 and 3) in the absence of objective clinical signs of disease, is highly implausible as evidenced by (1) the lack of antibiotic resistance in this genus [39, 40, 310], (2) the lack of correlation of persist”
- Lyme borreliosis: clinical case definitions for diagnosis and management in Europe. (2011, background): “Various double-blind, placebo-controlled studies have so far failed to support the idea that persistence of borrelial infection is the cause of such symptoms and have failed to show any sustained benefit from prolonged treatment with antibiotics [55–60].”
- Diagnosis of Lyme Borreliosis (2005, background): “Blood cultures are also negative in patients with persistent subjective symptoms following completion of an appropriate course of antibiotic treatment (154, 191).”