Statistical Significance for Genome Wide Studies Under Unequal Variance

By J. O'Day. 2015

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Patterns of phenotypic plasticity and local adaptation in the wide elevation range of the alpine plant Arabis alpina (2018, methodology): “To control for false discovery rate, the distribution of p-values were further transformed into q-values using the Storey & Tibshirani (2003) algorithm.”
A survey of best practices for RNA-seq data analysis (2016, background): “One challenge of this approach is the computational burden, as billions of gene – SNP associations need to be tested; bootstrapping or permutation-based approaches [133] are frequently used [134, 135].”