Gold Nanoparticles for Biology and Medicine

By D. Giljohann, D. Seferos, Weston L. Daniel, Matthew D. Massich, Pinal C. Patel, Chad A. Mirkin. Angewandte Chemie, 2010

2,207 citations recorded by the source corpus.

Gold colloids have fascinated scientists for over a century and are now heavily utilized in chemistry, biology, engineering, and medicine. Today these materials can be synthesized reproducibly, modified with seemingly limitless chemical functional groups, and, in certain cases, characterized with atomic-level precision. This Review highlights recent advances in the synthesis, bioconjugation, and cellular uses of gold nanoconjugates. There are now many examples of highly sensitive and selective assays based upon gold nanoconjugates. In recent years, focus has turned to therapeutic possibilities for such materials. Structures which behave as gene-regulating agents, drug carriers, imaging agents, and photoresponsive therapeutics have been developed and studied in the context of cells and many debilitating diseases. These structures are not simply chosen as alternatives to molecule-based systems, but rather for their new physical and chemical properties, which confer substantive advantages in cellular and medical applications.

Subfields: Electronic, Optical and Magnetic Materials, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f830d799f75659faed3b2e017708de3d06487875

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In Electronic, Optical and Magnetic Materials

1. Ajay Singh
2. Robert Langer
3. Khadijah A Altammar
4. H. Häkkinen
5. V. Mody
6. R. Siwale
7. H. Mody

In Molecular Biology

1. Robert Langer
2. Dabing Zhang
3. Priyanka Singh
4. H. Häkkinen
5. O. Farokhzad

Citations in the corpus

• The gold-sulfur interface at the nanoscale. (2012, background): “Although the synthesis yields appreciable amounts of a series of (n,m) clusters such as (10,10), (11,11), (12,12), (15,13), (18,14), (22,16), (22,17), (25,18), (29,20), (33,22), (35,22), (38,24), (39,24), most of them decay on a timescale of a few days either to polymeric (n,n) forms or into (25,18)”
• Biological Synthesis of Nanoparticles from Plants and Microorganisms. (2016, background): “Recently, the diverse applications of metal nanoparticles have been explored in biomedical, agricultural, environmental, and physiochemical areas (Figure 1) [1–5].”
• Nanowired three dimensional cardiac patches (2011, methodology): “and have been used in drug delivery, imaging and cancer therap”