Total and specific IgE in nasal polyps is related to local eosinophilic inflammation.
By C. Bachert, P. Gevaert, G. Holtappels, S. Johansson, P. V. van Cauwenberge. Journal of Allergy and Clinical Immunology, 2001
687 citations recorded by the source corpus.
Subfields: Immunology and Allergy, Otorhinolaryngology, Surgery
View Paper: https://www.semanticscholar.org/paper/f777ba8c48f66e2e264ef7f79eeb6b0d65e8a48b
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- James A. Hadley
- S. Johansson
Citations in the corpus
- Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial. (2016, background): “These microbes produce high-molecularweight enterotoxins known to function as superantigens that can potently stimulate lymphocytes (12).”
- Differentiation of chronic sinus diseases by measurement of inflammatory mediators (2006, background): “aureus enterotoxins and consecutive polyclonal IgE formation has been demonstrated in NP tissue, which correlates with markers of eosinophilic inflammation, pointing to a possible modifying role of bacterial superantigens in the pathophysiology of NP (26, 27).”
- A revised nomenclature for allergy: An EAACI position statement from the EAACI nomenclature task force (2001, background): “One example is the enterotoxins of Staphylococcus aureus, sometimes referred to as ‘‘superantigens’’, that seem to be capable of stimulating eosinophilic inflammation and a polyclonal IgE response in ‘‘atopic dermatitis’’ (53) and also in typically nonallergic nasal polyps (8).”
- Adult Chronic Rhinosinusitis: Definitions, Diagnosis, Epidemiology, and Pathophysiology (2003, background): “antibody levels in inferior turbinate tissue were greater than those from normal controls.(105) Curi-”
- Rhinosinusitis: Establishing definitions for clinical research and patient care (2004, positive): “Furthermore, an imbalance of MMPs with an upregulation of MMP-7 and MMP-9 in CRSwNP has been found, whereas in CRSsNP MMP-9 and TIMP-1, a natural antagonist, are increased.218 This results in the enhancement of MMP-9 in CRSwNP, whereas in CRSsNP MMP9 activity is inhibited.219 Differences in TGF-b1 a”