Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool
By D. Heyland, R. Dhaliwal, Xuran Jiang, A. Day. Critical Care, 2011
760 citations recorded by the source corpus.
IntroductionTo develop a scoring method for quantifying nutrition risk in the intensive care unit (ICU).MethodsA prospective, observational study of patients expected to stay > 24 hours. We collected data for key variables considered for inclusion in the score which included: age, baseline APACHE II, baseline SOFA score, number of comorbidities, days from hospital admission to ICU admission, Body Mass Index (BMI) < 20, estimated % oral intake in the week prior, weight loss in the last 3 months and serum interleukin-6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) levels. Approximate quintiles of each variable were assigned points based on the strength of their association with 28 day mortality.ResultsA total of 597 patients were enrolled in this study. Based on the statistical significance in the multivariable model, the final score used all candidate variables except BMI, CRP, PCT, estimated percentage oral intake and weight loss. As the score increased, so did mortality rate and duration of mechanical ventilation. Logistic regression demonstrated that nutritional adequacy modifies the association between the score and 28 day mortality (p = 0.01).ConclusionsThis scoring algorithm may be helpful in identifying critically ill patients most likely to benefit from aggressive nutrition therapy.
Subfields: Critical Care and Intensive Care Medicine, Nutrition and Dietetics, Physiology
View Paper: https://www.semanticscholar.org/paper/f67911d6a6860d8ddb39a87bcb9a7c29c5f1f441
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In Nutrition and Dietetics
Citations in the corpus
- Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) (2009, background): “Two prospective nonrandomized studies show that patients at high nutrition risk are more likely to benefit from early EN with improved outcome (reduced nosocomial infection, total complications, and mortality) than patients at low nutrition risk.(13,18) While widespread use and supportive evidence a”
- Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). (2009, background): “Two prospective nonrandomized studies show that patients at high nutrition risk are more likely to benefit from early EN with improved outcome (reduced nosocomial infection, total complications, and mortality) than patients at low nutrition risk.(13,18) While widespread use and supportive evidence a”
- ESPEN guideline on clinical nutrition in the intensive care unit. (2019, neutral): “The final composite NUTRIC score was correlated with mortality and the expected advantage of the score was to be able to show interaction between the score and nutritional intervention regarding outcome, hypothesizing that nutritional support might decreasemortality in patients with a high NUTRIC sc”